Football Is Sexy brings bold NFL Week 1 predictions with DraftKings betting odds, ESPN win probabilities, and our panel’s fearless instincts. See who we’re picking for every game.
Ladies, it’s time. Preseason is over. The lashes are curled, the jerseys are fitted, and the champagne is chilled. The NFL is back — and so is Football Is Sexy.
The NFL season is officially back, and the Football Is Sexy (FIS) team is ready to deliver their NFL Week 1 predictions with a bold, feminine, and unapologetic twist. While sportsbooks like DraftKings provide the betting odds and ESPN’s Matchup Predictor gives us the analytics, the FIS crew adds something those numbers can’t capture — intuition, experience, and instincts only true football-obsessed women bring to the game.
How Football Is Sexy Breaks Down NFL Predictions
At Football Is Sexy, our approach to predictions goes beyond just quoting the spread or percentages. We give fans a three-part breakdown:
Betting Odds (DraftKings)
Point spreads, moneylines, and over/unders that show how Vegas is setting the stage.
ESPN Win Probabilities
The analytics-driven percentages from ESPN’s Matchup Predictor that forecast each team’s chances.
FIS Instincts & Picks
Our panel’s personal game-day predictions, fueled by passion, football knowledge, and a little lipstick-stained luck.
It’s the combination of data and intuition that makes FIS different. Because football isn’t just about numbers — it’s about energy, momentum, and sometimes, gut feeling.
Meet the Football Is Sexy Panel
Monica Madrid (FIS CEO) – Die-hard 49ers fan and season ticket holder who once got surprised Super Bowl tickets from Jerry Rice on The Kelly Clarkson Show. She even helped co-write a song for Brock Purdy’s country line dancing commercial, bringing heart, history, and creativity to every pick.
Tasha Macri (FIS CMO) – Fell in love with football dancing on the sidelines, worked at a sports bar in college so she could get paid to watch the game, & worked events with Joe Montana, ’03 Super Bowl Bucs, & Marcus Maye…where she realized this was the career she wanted.
Amber Phillips (FIS COO) – Fantasy football trailblazer, the first female employee at Fantasy Football Advice Network, and host or co-host of several FFAN shows. A regular panelist at the Fantasy Football Expo, she brings knowledge, strategy, and plenty of sass to every game.
Why Our Predictions Hit Different
While sportsbooks and ESPN models provide valuable insights, the FIS team gives fans a more complete picture:
- Vegas sets the odds to balance betting, not predict winners.
- ESPN analytics crunches probabilities, but percentages can’t measure clutch moments.
- FIS instincts factor in emotion, rivalry heat, momentum shifts, and the kind of football truths you only learn from living and breathing the game.
By putting all three together, we offer NFL Week 1 predictions that are smart, sexy, and fan-friendly.
NFL Week 1 Coverage
From the Cowboys vs. Eagles Thursday night opener to the Vikings vs. Bears Monday night showdown, the FIS crew will break down every game with:
- Vegas betting odds
- ESPN win probabilities
- Our panel’s fearless picks
Whether you’re betting, setting your fantasy lineup, or just want to flex your football knowledge, our predictions keep you covered.
Thursday, Sept. 4
Cowboys @ Eagles
- Odds: Eagles -8.5 | O/U 47.5
- ESPN Predictor: Eagles 66.4% | Cowboys 33.3%
- FIS Picks: Monica – Eagles | Amber – Eagles | Tasha – Eagles
💄 Verdict: Philly’s flying high, and even the analytics agree.
Friday, Sept. 5
Chiefs @ Chargers
- Odds: Chiefs -3 | O/U 45.5
- ESPN Predictor: Chiefs 56.9% | Chargers 42.8%
- FIS Picks: Monica – Chiefs | Amber – Chiefs | Tasha – Chargers
💄 Verdict: Mahomes is still the prince of prime time, but Tasha sees an upset brewing in L.A.
Sunday, Sept. 7 — Early Games
Raiders @ Patriots
- Odds: Patriots -2.5 | O/U 43.5
- ESPN Predictor: Patriots 51.9% | Raiders 47.7%
- FIS Picks: Monica – Patriots | Amber – Raiders | Tasha – Raiders
💄 Verdict: Practically a toss-up. FIS leans Vegas love.
Steelers @ Jets
- Odds: Steelers -3 | O/U 38.5
- ESPN Predictor: Steelers 58.8% | Jets 40.9%
- FIS Picks: Monica – Steelers | Amber – Steelers | Tasha – Jets
💄 Verdict: Analytics back Pittsburgh, but Tasha is all in on gang green swagger.
Dolphins @ Colts
- Odds: Colts -1.5 | O/U 47.5
- ESPN Predictor: Colts 49.9% | Dolphins 49.7%
- FIS Picks: Monica – Dolphins | Amber – Colts | Tasha – Colts
💄 Verdict: This game is basically 50/50 everywhere. Bring your popcorn.
Cardinals @ Saints
- Odds: Cardinals -6.5 | O/U 43.5
- ESPN Predictor: Cardinals 57% | Saints 42.7%
- FIS Picks: Monica – Cardinals | Amber – Cardinals | Tasha – Cardinals
💄 Verdict: Unanimous. Cards win and cover.
Giants @ Commanders
- Odds: Commanders -5.5 | O/U 45.5
- ESPN Predictor: Commanders 69% | Giants 30.7%
- FIS Picks: Monica – Commanders | Amber – Commanders | Tasha – Commanders
💄 Verdict: Washington dominance written all over this one.
Panthers @ Jaguars
- Odds: Jaguars -3.5 | O/U 46.5
- ESPN Predictor: Jaguars 58.9% | Panthers 40.8%
- FIS Picks: Monica – Jags | Amber – Panthers | Tasha – Jags
💄 Verdict: The cats claw, but Jacksonville’s favored…Monica and Tasha ride with the big cats.
Bengals @ Browns
- Odds: Bengals -5.5 | O/U 47.5
- ESPN Predictor: Bengals 65.2% | Browns 34.5%
- FIS Picks: Monica – Bengals | Amber – Bengals | Tasha – Bengals
💄 Verdict: Joe Burrow has the room and the ladies in lockstep.
Buccaneers @ Falcons
- Odds: Buccaneers -2.5 | O/U 47.5
- ESPN Predictor: Buccaneers 55.3% | Falcons 44.4%
- FIS Picks: Monica – Bucs | Amber – Bucs | Tasha – Bucs
💄 Verdict: All Buccaneers. Atlanta has the home crowd, but Vegas and ESPN say Bucs too.
Sunday, Sept. 7 — Late Games
Titans @ Broncos
- Odds: Broncos -7.5 | O/U 42.5
- ESPN Predictor: Broncos 69.8% | Titans 29.9%
- FIS Picks: Monica – Broncos | Amber – Broncos | Tasha – Broncos
💄 Verdict: Thin air, thick odds. Denver rolls.
49ers @ Seahawks
- Odds: 49ers -2.5 | O/U 43.5
- ESPN Predictor: 49ers 53.7% | Seahawks 45.9%
- FIS Picks: Monica – 49ers | Amber – Seahawks | Tasha – 49ers
💄 Verdict: Monica’s Niners edge it out in both analytics and odds. Amber’s the rebel here.
Lions @ Packers
- Odds: Packers -2.5 | O/U 46.5
- ESPN Predictor: Lions 51.9% | Packers 47.7%
- FIS Picks: Monica – Packers | Amber – Lions | Tasha – Lions
💄 Verdict: ESPN leans Lions, Vegas leans Packers. FIS splits. Drama guaranteed.
Texans @ Rams
- Odds: Rams -3 | O/U 43.5
- ESPN Predictor: Rams 56% | Texans 43.7%
- FIS Picks: Monica – Texans | Amber – Rams | Tasha – Texans
💄 Verdict: FIS is spicy here, two on Houston despite analytics pointing L.A.
Ravens @ Bills
- Odds: Bills -1.5 | O/U 50.5
- ESPN Predictor: Bills 52.3% | Ravens 47.3%
- FIS Picks: All three – Ravens
💄 Verdict: Analytics like Buffalo. FIS is all in on Baltimore. Let’s see who flirts with destiny.
Monday, Sept. 8
Vikings @ Bears
- Odds: Vikings -1.5 | O/U 43.5
- ESPN Predictor: Bears 52.5% | Vikings 47.1%
- FIS Picks: Monica – Bears | Amber – Vikings | Tasha – Bears
💄 Verdict: Analytics back Chicago, but this one’s tight. Split panel = pure MNF drama.
Final Whistle
Vegas has its odds. ESPN has its percentages. But here at Football Is Sexy, we’ve got intuition, experience, and just the right amount of lipstick-stained luck. Who’ll come out on top — the sportsbooks, the computers, or the women who know that football is more than a game?
Either way, babes, football is officially back. And yes… it’s still sexy. 💋🏈
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